News Archives - 2004

 

July  News

 

 
 

Full steam ahead?

Indian scientist among five winners of Jefferson awards

Project promotes domestic intellectual property rights

PHARMACEUTICALS - ABBOTT DEFENDS NORVIR PRICE HIKE

NFC generates cumulative surplus of Rs 631.7 cr

N-power sector may be opened up — Changes to Atomic Energy Act await Cabinet nod

Boeing, ISRO to build satellite

Biocon's Cuban JV adds 5 drugs

Developments in International IP Regime

Ministry Seeks Rebate To Promote Pharma R&D

Special 301 Report Identifies Countries With Lax IP Protections

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Full steam ahead?

Jun 3rd 2004
From The Economist print edition



Superconductors are starting to become useful

A WAG once said of Brazil that it is tomorrow's country, and always will be. Superconductivity frequently suffers similar jibes. On the face of things, a technique that allows electricity to be transmitted without resistance should be ubiquitous. But the obstacles have proved insurmountable for all but niche applications, such as medical imaging.

 

Three things stand in the way of the wider use of superconductors. First, they need to be cooled well below room temperature. Second, those that need the least cooling are the most difficult to work with. Third, the passage of an electric current creates magnetism, and magnetism tends to destroy superconductivity.

 

But these obstacles are being overcome. As a result, superconductivity is starting to appear in applications as diverse as telecoms and electric motors. There is even talk of reaching superconductor nirvana: using them for controlling and transmitting large amounts of electrical power.

 

The future's taped

 

Superconductor Technologies, a company based in Santa Barbara, California, is building superconducting filters for mobile-phone base stations. In common with all the other putative mass-market applications of superconductivity, the materials in question are so-called high-temperature superconductors (HTSs). High-temperature is a relative concept. These materials need to be cooled with liquid nitrogen (a mere -196°C). But that is cheap compared with the liquid helium (-269°C) used to cool traditional superconductors, such as those employed in medical imaging. There is, however, a price to pay. HTSs are ceramics, and thus much harder to shape and work than traditional superconductors, which are metals. This difficulty is an especially important factor when what is required is something that will do the same job as a traditional wire.

 

Superconducting Technologies' devices, though, are not wires. They are chips with superconducting surfaces. No flexion is involved, so using rigid ceramics is not a problem. The superconductor's lack of resistance allows the firm to build filters that can chop a signal into much narrower frequency bands than a traditional filter. This, in turn, translates into improved performance. In a recent test on a commercial network, using superconducting filters increased that network's capacity by half.

 

Mobile-phone networks are an important market, but a specialised one. The hope in the industry is that HTSs will be taken up in more traditional, but bigger electrical-engineering applications. This is the sort of thing that American Superconductor, a firm based in Westborough, Massachusetts, is working on.

 

American Superconductor believes it has cracked the most difficult fabrication problem of HTSs, turning them into the equivalent of wire. Ceramics cannot be drawn in the way that metal is. Instead, American Superconductors and its rivals powder the stuff and pack it into silver tubes. The tubes, being metallic, can be drawn. They can also be plaited together to form cables, heated to improve the contact between the superconducting grains, and rolled flat. The result is flexible tapes that can be used in a similar way to wires.

 

One application of these tapes is in electric motors. And, as is often the way with new technologies in America, the government has conveniently created a market opportunity. It did so by announcing four years ago its intention to convert the country's navy to a fleet powered by electric motors.

 

Accordingly, American Superconductor has been using its tape to build superconducting motors. The first, a small one producing 5 megawatts, was delivered to the navy a year ago, and has completed its tests successfully. As a result, a 36.5 megawatt motor will be delivered next year. This motor is easily big enough to propel a destroyer (it is just a tad less powerful than were the engines of the Titanic). But, according to Greg Yurek, American Superconductor's boss, it will be a third of the weight of its conventional alternative.

 

American Superconductor is also starting to infiltrate another area of heavy electrical engineering: power transmission. The first application the firm has in mind is a niche in this market, but it is an important one: stabilising the grid in order to prevent power failures. In January, the firm installed a prototype “synchronous condenser” designed to provide this stability to an electrical sub-station in Tennessee. Large-scale electricity transmission usually uses alternating current, in which both current and voltage oscillate. Crashes occur when the two get out of sync. The condenser's job is to stop this happening.

 

American Superconductor and its competitors are also engaged in a race to make superconducting tape that could be used to carry power on the grid itself. The challenge here is twofold. The first is to create tapes that can support large currents undisturbed by the magnetic fields those currents create. The second is to scale up the processes by which the tapes are made, to allow mass production.

 

The current record-holder for current, as it were, is SuperPower, a firm based in Schenectady, New York. In March, it transmitted 120 amps over a distance of 50 metres—three times better than the best previous result. The trick in this tape—and other so-called “second-generation” tapes—is that a thin layer of the superconducting ceramic is sandwiched between two layers of metal. Such a thin layer alters the current flow in a way that reduces the current's susceptibility to magnetic interference. It also results in a tape that costs a third to a fifth as much to make.

 

SuperPower is now scaling up its production capacity. By next year it should be able to make cables a third of a kilometre long. It plans to use one of these to connect two sub-stations in Albany, New York. Shorter, experimental segments have already been tried elsewhere, but the significance of the Albany project is that it will be using superconducting cables in a completely commercial environment. Then, perhaps, superconductivity's tomorrow will truly have arrived.

 

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Indian scientist among five winners of Jefferson awards


TIMES NEWS NETWORK
[ MONDAY, JUNE 07, 2004 12:51:26 AM ]

 

WASHINGTON: An Indian scientist in Massachusetts is among five winners of the Jefferson Science Fellowships awarded by the US State Department.

 

Dr Kalidas Shetty, an associate professor of food biotechnology at the University of Massachusetts at Amherst, and four others attended a ceremony at the State Department recently, where they were greeted by Secretary of State Colin Powell. “Over the coming year, these five individuals will be our scientific advisers and educators. They will bring fresh ideas and new perspectives to America's foreign policy,” he said.

 

The other four Jefferson Science Fellows are: Dr. Julian Adams of Michigan University, Dr. Bruce Averill of Toledo University; Dr. Melba Crawford of the Texas University at Austin; and Dr. David Eston of California. At the ceremony, Powell said that the Jefferson program gives the State Department the opportunity to benefit from the counsel and experience of featured academic scientists. Shetty, who has a Ph.D. from the University of Idaho, holds several patents.

 

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Project promotes domestic intellectual property rights
Qin Chuan
2004-05-31 06:38

 

Chinese pharmaceutical companies are making progress in terms of intellectual property rights protection.

 

At least four new medicines developed under a key national project have received approval from the State Food and Drug Administration since 2002, when the project was launched to encourage innovation of new medicines and the modernization of the traditional Chinese medicine industry.

 

Intellectual property rights of the four medicines are owned by Chinese researchers and pharmaceutical companies, according to Yang Zhe, head of the biomedicine division of the Ministry of Science and Technology. Meanwhile, more than 20 new medicines have entered the stage of clinical experiments, Yang said.

 

Xiao Shiying, an official with the administrative centre for Agenda 21, China's centre for UN's global development project, said nearly 60 traditional Chinese medicines are being developed under the project.

 

Currently few of the medicines have been finished, Xiao said, but some are expected to be approved by the State Food and Drug Administration next year.

 

"The awareness of intellectual property right protection in the traditional Chinese medicine industry is far from enough," said Cai Zhongde, with the institute of traditional Chinese medicines at the Chinese Academy of Traditional Chinese Medicine.

 

Meanwhile, the technological strength of Chinese companies and research institutes is weak and therefore innovation is difficult to achieve, he said.

 

Although the number of patented traditional Chinese medicines has risen in recent years, the number of completely innovated ones remains relatively small, Cai said.

 

Yang said China began to pay more attention to the development of patented medicines in the Ninth Five-Year Plan (1996-2000). But it was not until the project was launched in 2002 that such an attempt was strengthened.

 

The project was launched by the Ministry of Science and Technology as one of the key national scientific and technological projects during the 10th Five-Year Plan (2001-05).

 

It is expected that the project will help transform the Chinese pharmaceutical industry from a "copier" to an "innovator."

 

The ministry hopes to see a group of compound synthetic medicines, herbal medicines and bio-engineered drugs developed, whose intellectual property rights will be owned by Chinese companies or researchers.

 

Statistics from GlaxoSmithKline (GSK), a leading pharmaceutical company, show China is the seventh largest pharmaceutical market in the world with a value of US$6.8 billion from drugs in 2002.

It is estimated China's medical market will be US$14 billion by 2006 and US$24 billion by 2010.

However, China's own pharmaceutical industry is weak in the research and development of new products because it has long depended on replicating imported drugs, insiders say.

 

At present, Chinese companies put only 2 per cent of their sales income into development, compared with more than 20 per cent by leading pharmaceutical companies in the world.

 

More than 6,700 drug companies produce about 1,300 types of synthetic medicines in China, 97 per cent of which, however, are generic medicines.

 

With its entry into the World Trade Organization, China has pledged its commitment to greater protection of intellectual property rights on medicines, and the domestic pharmaceutical industry is expected to face more challenges.

 

(China Daily 05/31/2004 page5)

 

 

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PHARMACEUTICALS
Chemical & Engineering News

May 31, 2004,  Volume 82, Number 22  p. 6


 

ABBOTT DEFENDS NORVIR PRICE HIKE
Consumer group seeks U.S. intervention over 400% increase for AIDS drug


 

RICK MULLIN



 

Abbott Laboratories defended the recent 400% price increase for its AIDS drug Norvir (ritonavir) before a government panel last week in an effort to forestall the issuance of licenses for generic versions of the drug under the 1980 Bayh-Dole Act.

Essential Inventions, a consumer advocacy group, has petitioned the Department of Health & Human Services to invoke the law, which ensures public access to government-funded inventions. Abbott had received a $3.5 million NIH grant for the development of Norvir. The drug, with 2003 sales of $95 million, is scheduled to come off patent in 2014.

Citing the expense of drug discovery and Norvir’s low cost compared with other treatments, Abbott upped the price of a 100-mg dose from $1.71 per day to $8.57 in December, sparking protest from AIDS activists. Jeffrey M. Leiden, president of Abbott’s pharmaceutical products group, told an NIH committee last week that the price hike does not affect government programs such as Medicaid and that uninsured patients can receive Norvir for free.

Leiden said Bayh-Dole is only applicable to inventions that have not been commercialized, arguing that the law “was never intended to be a mechanism to determine prices.” He noted that the federal grant covered less than 1% of Norvir’s development cost of more than $300 million.
Former senator Birch Bayh, an author of Bayh-Dole, supported Leiden’s view before the committee, specifically cautioning against the use of the law to control drug prices.

Essential Inventions founder James Love argued that Abbott is not making Norvir available to the public on “reasonable terms” as required under Bayh-Dole. “The facts in the Abbott case are so extreme that a ‘sky is the limit’ or ‘anything goes’ precedent will have been set,” he said.

 

 

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NFC generates cumulative surplus of Rs 631.7 cr

 

Hyderabad , June 19

 

THE Nuclear Fuel Complex (NFC), a Department of Atomic Energy (DAE) undertaking, has generated a net cumulative surplus of Rs 631.7 crore for the exchequer.

For the financial year ended March 31, NFC's revenues stood at Rs 710.35 crore (Rs 776.58 crore) as against an expenditure of Rs 447.94 crore (Rs 589.23 crore).

The annual revenue receipts were in the range of Rs 624 crore to Rs 823 crore, far exceeding annual expenditures that were in the range of Rs 399 crore to Rs 589 crore. A lesser plant load factor of reactors resulted in a dip in revenues recently.

Giving these details at a press conference, Dr C. Ganguly, Chairman and Chief Executive of NFC, said the NFC has embarked on a major expansion to meet the increasing demands from the nuclear power sector. It supplies fuel bundles and core components for nuclear reactors.

While the 1,200-acre Palayakkayal (near Tuticorin) Zirconium sponge production unit will be completed in three years, NFC's third unit will come up at Jaduguda in Jharkand State at an estimated cost of Rs 286 crore, Dr Ganguly said.

The expansion was part of NFC's plan to meet the targets set by the department to achieve 20,000 MW power generation by 2020.

He said the NFC had crossed a major milestone of manufacturing three lakh fuel bundles, made of natural uranium oxide pellets and enwrapped in zircaloy pipes, for nuclear reactors in the country.

While the 19-element fuel bundle (for 220 MW units) carries 15 kg of high-density uranium oxide pellets that can generate 6.40 lakh units of electricity, the 37-element bundle (for 540 MW units) carries 22 kg of pellets capable of producing 9.26 lakh units of electricity.

"It took 20 years to produce one lakh fuel bundles, while it took just seven more years to reach the two-lakh landmark and three years for reaching the three-lakh mark," Dr Ganguly said.

Power of nuclear energy: Strongly advocating for nuclear energy, Dr Ganguly said nuclear option ensured affordable, sustainable power supply. Nuclear power held good promise keeping in view the increased preference for non-carbon based energy sources.

"The deposits, if fully utilised, could result in an installed capacity of 350 GW providing power for 1,000 years," Dr Ganguly said.

"There are 14 basins that comprise nuclear resources. We tapped only two so far," he said.

Strongly recommending for taking up the Nalgonda Uranium project (in Cuddapah basin), he said it suited well because of better logistic facilities.

Meanwhile, Dr Ganguly has been appointed as a Director of Nuclear Fuel Cycle at the International Atomic Energy Agency. He is expected to take up the new assignment in August.

Mr R. Kalidas, a Deputy Chief Executive with the Complex, will replace Dr Ganguly. At present, Mr Kalidas is the in-charge of NFC's Tubes Group.

 

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N-power sector may be opened up — Changes to Atomic Energy Act await Cabinet nod

Business Line,T.S. Subramanian

Chennai , June 21

A TOTAL review of the Atomic Energy Act is under way to find out areas where modifications are required to enable private participation, both by Indian or foreign companies, for the construction of nuclear power projects in the country, according to Mr S.K. Jain, Chairman and Managing Director, Nuclear Power Corporation of India Ltd (NPCIL). The Atomic Energy Act controls nuclear activities in the country.

Speaking to Business Line , Mr Jain said, ``As per my understanding and knowledge, modifications to the Atomic Energy Act have already been drawn up. They have been reviewed by various ministries and are ready for consideration by the Union Cabinet. Subsequently, Parliament will consider these amendments to the Act.''

``We are hoping that by this year-end the amendments to the Act will be passed by Parliament paving the way for joint venture, (even) 100 per cent private participation in building nuclear power plants in the country.''

Mr Jain stressed that there would, however, be ``built-in clauses'' in the Act which would entail that regulatory aspects connected to sensitive nuclear material and issues of safety would be ``totally under the purview of the Department of Atomic Energy (DAE) and the Atomic Energy Regulatory Board (AERB).''

AERB is the watchdog body that monitors safety in nuclear power plants in the country. It is in overall control of safety of nuclear power plants in the country.

``AERB will be playing the same role from siting to decommissioning of the private plants. DAE will have total control over the nuclear material. Whatever nuclear material is being purchased and used, it will be under the command of DAE so that they will be effectively regulated,'' Mr Jain said.

 

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Boeing, ISRO to build satellite

PTI
[ TUESDAY, JUNE 22, 2004 06:57:52 PM ]

 


 

BANGALORE: Boeing and Indian Space Research Organisation are set to jointly build a two-tonne satellite for the international market with the American firm getting the nod from the United States government, key US and Indian officials indicated on Tuesday.

"Our government recently approved a licence authorising Boeing Satellite Systems to engage in discussions and share data with ISRO on the division of responsibilities for possible joint cooperation in the development and marketing of communication satellites," US under secretary of Commerce Kenneth I Juster said.

Juster stated this during the course of his speech to the India-United States Conference on space science, applications and commerce, here.

When reporters later sought details, he reiterated the statement, saying he was doing so with the consent of both parties (Boeing and ISRO) but declined to elaborate pointing out that US Government did not comment on individual cases